10-K · February 25, 2026
Pacific Biosciences positions itself as a leader in HiFi long‑read sequencing, pursuing growth by lowering per‑sample cost (SPRQ‑Nx), driving Revio adoption, expanding Vega and kitted solutions (Kinnex, PureTarget), and…
Earnings analysis · 10-Q
Filed May 8, 2026 · Our reading of the company's report
The latest report
PacBio's Q1 2026 10-Q reveals ongoing challenges with revenue and profitability, marked by revenue of $37.18 million, which fell short of estimates and reflects minimal YoY growth. Notably, the company achieved…
PacBio's Q1 2026 10-Q reveals ongoing challenges with revenue and profitability, marked by revenue of $37.18 million, which fell short of estimates and reflects minimal YoY growth. Notably, the company achieved significant gross profit improvement, shifting from a gross loss to a $12.8 million profit, driven by optimized costs and restructuring efforts. Management expresses cautious optimism for future growth, anticipating increased revenue contributions from key segments in subsequent quarters.
How much of each revenue dollar the business keeps.
One point per quarterly or annual filing. Both margins are shares of that report's revenue.
The business segments reported by the company.
Shares of the segments disclosed in this filing, largest first.
Our analysis across the last few reports.
Our model's reading of each filing, not the share price or the market's reaction. Annual and quarterly reports each occupy one position.
Reported revenue of $37.18M fell short of consensus estimate of $40.18M.
Gross profit increased to $12.8M from a gross loss of $1.4M YoY.
Operating expenses decreased by $406.4 million, reducing the operating loss significantly.
Net cash proceeds of approximately $48.1 million received from asset sale to Illumina.
Cash and cash equivalents totaled $276 million, showing a slight decline from previous quarter.
Management expects growth in consumables due to expanded Revio and Vega adoption.
Litigation expenses of $15.4 million impacted Q1 operating costs.
Q1 cash used in operations totaled $44.69M, continuing a trend of negative cash flow.
Prolonged sales cycles due to tighter funding could constrain revenue growth in future quarters.
Management expects full-year revenue guidance in the range of $165M to $175M.
Pacific Biosciences positions itself as a leader in HiFi long‑read sequencing, pursuing growth by lowering per‑sample cost (SPRQ‑Nx), driving Revio adoption, expanding Vega and kitted solutions (Kinnex, PureTarget), and…
Q2 2025 showed operational improvement: revenue rose to $39.8M (Q2 2025) from $36.0M (Q2 2024), gross margin expanded to ~36.9% from ~16.5%, and diluted loss per share narrowed to $(0.14) from $(0.64). However, balance…
PacBio reported Q3 revenue of $39,967,000 (Q3 2023: $55,691,000), a 28.2% YoY decline, gross profit of $10,004,000 (gross margin ~25.0%) and a net loss of $60,725,000 (EPS -$0.22). Management recorded a $93,200,000…
Q1 2024 revenue was essentially flat at $38.81M versus $38.90M a year ago, while gross profit improved to $11.28M (29.06% margin) and operating loss narrowed to $(81.36)M. Net loss was $(78.18)M or $(0.29) per share, an…
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